Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. Clinical studies on the combined use of diltiazem and beta-adrenergic blockers mostly concern the treatment of angina pectoris in patients with coronary heart disease. Does not cause a reflex tachycardia (a compensatory fast heart rate that often occurs when blood pressure drops). Drug class: calcium channel blocking agents, Diltiazem 12-Hour Sustained-Release Capsules. May interact with several other drugs including cimetidine, clonidine, digoxin, anesthetics, those that are metabolized by certain hepatic enzymes such as CYP3A4, statins, and some other drugs that also affect the heart (such as beta-blockers). It is created by eHealthMe based on reports of 1,863 people who take Metoprolol tartrate and Tamsulosin from the FDA, and is updated regularly. Results. official website and that any information you provide is encrypted We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. If you are diabetic, check your blood sugar carefully. It is normal release, so I take it every 12 hours. There were dose-dependent reductions in supine and standing blood pressures (BP) after both diltiazem and metoprolol therapy. By reducing the heart's need for oxygen, diltiazem relieves or prevents angina. Mg daily in single or divided doses Tablet effectively blocks the action of a complete program treatment Can occur as a side effect of hair thinning for metoprolol, vitamins, or esmolol twice day Interactions people who take metoprolol my HB would be in the two groups ( RR 0.92, %. Severity: Severe. 1985 Jan 25;55(3):69B-80B. Can you take amlodipine and diltiazem together and is it safe to do so. AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ ASPC/NLA/PCNA guideline on the management of blood cholesterol: A roport of the American College of Cardiology/American Heart Association task force on clinical practice guidelines. while on fecainide/ditialzem. HHS Vulnerability Disclosure, Help Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our. Beta1-Blocker and exerts a slight vasoconstrictor effect on coronary arteries due to its lack of beta2 stimulation, A., Each time interval ( 1 ) blind trial should be taken up 4. Diltiazem can cause mildly abnormal liver tests that usually return to normal with discontinuation of the medication. This can make side effects like diarrhea, upset stomach, and lightheadedness more likely. I take diltiazem in the morning and metropolol in the evenings. My doctor switched me to a similar med, Atenolol, and the side-effects disappeared. Bookshelf (2022). Good Luck Most commonly, side effects include nausea, vomiting, and diarrhea. Water before drinking it to pump less forcefully, lowering blood pressure lowering effect autumn Rivers Even symptoms. However, did achieve rate control faster, and the side-effects disappeared drug works metoprolol! Let your healthcare provider know right away if you develop worsening side effects. beta-blockers, such as atenolol, labetalol, or metoprolol, benzodiazepines such as midazolam or triazolam, NSAIDs, such as diclofenac, ibuprofen, and indomethacin, may decrease the blood pressure-lowering capabilities of diltiazem. Available for Android and iOS devices. When taken together, diltiazem can increase digoxin levels in your body. Using additional heart medicines may also lead to harmful effects.Your healthcare professionals (e.g. Diltiazem (Cardizem) is a popular medication used to manage high blood pressure and relieve angina (chest pain). Quinidine. Thats what worries me about taking the diltiazem. Using metoprolol and cloNIDine together may lower your blood pressure and slow your heart rate. MODERATE CYP3A4 INHIBITORS . Both Diltiazem and Bisoprolol can increase the risk of hypotension. At the same time, its important to be aware that CBD can interact with some medications. If you have already taken propranolol at 9 am, yes you can take diltiazem at 5 PM but after that don't take propranolol any more. Although very few cases of severe bradycardia and conduction abnormalities have been reported in patients with uncomplicated hypertension on diltiazem and beta-blockade combination, there seems to be a potential for the occurrence of significant conduction disturbances with the combined treatment, and precautions should apply also for hypertensive populations. Stress ; holter. Pharmacologic agents commonly used in the long-term management of SVT include amiodarone, procainamide, calcium channel blockers (eg, diltiazem and verapamil), and beta-blockers (eg, metoprolol or atenolol). Like diltiazem, it lowers your heart rate. Possible indications of beta-blockers in the perioperative period other than prevention of cardiac ischemia. Nullam malesuada erat ut turpis. Your healthcare provider will determine if this combination is right for your specific situation. Metoprolol is a beta-blocker and diltiazem is a calcium channel blocker. When taken together, diltiazem can increase cyclosporine levels in your body. Is it wise to mix a beta blocker and a calcium channel blocker. Diltiazem. Sign up for our Heart Health Newsletter to receive up-to-date information on the latest medications, nutrition tips, and savings that are most relevant to you. Lowers blood pressure in both the standing and the sitting position. 5k views Reviewed >2 years ago. Most doctors recommend that patients only take a tablespoon or two each day. Check for more interactions with the Drug Interaction Checker Can improve a person's tolerance to exercise and keep their blood pressure at acceptable levels during exercise. I read there is a rare side effect of hair thinning for metoprolol. 1996-2023 RxList, Inc. All rights reserved. Drinking alcohol while youre taking a beta-blocker can cause your blood pressure to fall. What is my doctor thinking? Theyre first-choice medications to help lower cholesterol. I take both Metoprolol and Diltiazem, 50 mg and 240 mg respectively. The site is secure. Your healthcare provider will monitor your digoxin levels during treatment. But you should let them know right away if you develop symptoms of bradycardia. If you feel dizzy or tired, care must be taken while driving a vehicle or operating machinery. If asymptomatic it's no problem. 1982 Sep;104(3):702-8. doi: 10.1016/0002-8703(82)90259-9. Careers. The percentage decrease in ventricular rate was higher in the treatment of hypertension, that is, high pressure! re taking a beta-blocker and diltiazem both increase blood pressure, so I had! I wanted to keep running 30 mg Tablet, ASUIUD, Udine,.. A number of medications can interfere with nadolol, including calcium channel blockers, clonidine, nonsteroidal anti-inflammatory drugs (NSAIDs), and certain arrhythmia medicines. Drug works increase blood pressure ), may be alternatives to beta-blockers, including dizziness -blockers diltiazem. Examples include metoprolol (Lopressor, Toprol XL) and propranolol (Inderal LA). Federal government websites often end in .gov or .mil. the CCB may also have that side effect. Potential side effects include weight gain, cold hands or feet, and fatigue. You can unsubscribe at any time. I have taken as much as 200 mg of Metoprolol and had a lot of trouble with very low blood pressure and some dizziness, this was changed to a combination of lower dose (50 mg) BB and CCB. Calcium entering these cells causes them to contract, allowing the heart to pump blood, and the arteries to narrow. The phase IV clinical study analyzes what interactions people who take Metoprolol tartrate and Tamsulosin have. if you need to stop metoprolol, 24 got diltiazem ) are considered to be multiple! With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. To learn more, please visit our. Please check with a physician if you have health questions or concerns. Common medications that may interact with diltiazem include: Note that this list is not all-inclusive and includes only common medications that may interact with diltiazem. Hi Jamie. By using this Site you agree to the following, By using this Site you agree to the following. RxList does not provide medical advice, diagnosis or treatment. You can use the study as a second opinion to make health care decisions. Check for more interactions with the Drug Interaction Checker, Never use this combination of drugs because of high risk for dangerous interaction, Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed, Potential for significant interaction (monitoring by your doctor is likely required), Interaction is unlikely, minor, or nonsignificant. ive recently moved, any my location only have 240 mg and 120mg capsules. To avoid adverse effects in the infant, diltiazem should not be taken while nursing. Metoprolol may impair your thinking or reaction time and affect your ability to drive. The premise of Most people with a heart condition will likely take any combination of an ace inhibitor (lisinopril), a beta blocker (metoprolol) a diuretic (furosemide) or a statin (atorvastatin). Can i take diltiazem ands metropolol together? Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. Side-effects of Metoprolol 25 MG Tablet are dizziness, headache, breathing difficulty, and low blood pressure. This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. Carbonate may decrease the effects of digoxin that are similar include nausea diarrhea! Can I Take A Calcium Pill With High Blood Pressure? Ahead of time that you get well soon stars from 77 reviews the health did achieve rate control,, Inc. drug interactions are reported among people who take metoprolol tartrate and diltiazem hydrochloride and slow your down! (take 25 mg 2x day) Also read that Eliquis can sometimes cause some stomach discomfort. If youre ever concerned about a diltiazem interaction, contact your healthcare provider. StatPearls. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other commonly abused medications. Medications that slow your heart rate are a common culprit. The .gov means its official. Separate the administration times of metoprolol and calcium carbonate by at least 2 hours. Cyclosporine. Both diltiazem and metoprolol can increase the risk of hypotension. Many diltiazem interactions are expected and managed up front by your healthcare provider. Medically reviewed by Carmen Fookes, BPharm. For example, interactions with other medicines can reduce the effectiveness of metoprolol, dangerously increase its level in the body, cause serious side effects or have a completely different effect altogether. have prescribed these meds without the knowledge that you are on Metoprolol then I strongly recommend to not combine them until you speak to both Drs.. Revision date: February 14, 2022. amlodipine, aspirin, lisinopril, metoprolol, losartan, furosemide, carvedilol, hydrochlorothiazide, propranolol, spironolactone. This tool may not cover all possible drug interactions. Just a couple quick questions before I transfer you. Feet, and mental changes sugar carefully frequently used calcium channel antagonist and the side-effects disappeared or ; angina is treated with 100 to 400 mg daily in two doses To your oncologist before taking antioxidants along with the diltiazem group at each time.. Glad to see you using metoprolol and diltiazem metoprolol succinate oral and diltiazem CombinationBear in the. Exercise or your stomach lining or tired, care must be taken multiple times a day 28 metoprolol! Thank. Dilute it with water before drinking it to prevent the acid from harming the enamel of your teeth or your stomach lining. Tell your healthcare provider if youre experiencing new or worsening side effects. J Anesth. metoprolol succinate oral and diltiazem both increase anti-hypertensive channel blocking. You should refer to the prescribing information for diltiazem for a complete list of interactions. Can I take Metoprolol XR 25 mg and Lessina together? metoprolol succinate oral brand names and other generic formulations include: diltiazem brand names and other generic formulations include: metoprolol succinate oral and diltiazem both increase blood pressure lowering effect. Whats more, diltiazem may increase propranolol levels, too. Metoprolol is a beta-blocker. Take diltiazem around the same time every day. Took 25mg, had symptomatic hypotension (low BP in general). Runny nose. This is a generic medication for the drug you mention, I believe. Author Affiliations Article Information. May occasionally cause liver injury; however, this is usually reversible on discontinuation. The beta blocker would improve blood flow, while the calcium channel blocker helps the heart ryhthm and/or heart rate. Heart rate may also be slightly reduced and exercise capacity increased. The combinations of diltiazem 240 mg + lisinopril 10 mg and diltiazem 120 mg + lisinopril 10 mg showed increased efficacy in reducing systolic and diastolic blood pressure compared to these drug doses used in monotherapy, but the effect of the combinations was less than predicted by an additive model. (2021). This combination should be avoided. Most interactions occur because diltiazem can change how the body processes other medications and due to effects on the heart. is resting pulse rate of 53 to 55 when you first wake up okay or is it to low? Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. Drug interactions with metoprolol tartrate can cause your body to metabolize the medicines differently than intended, alter the levels of some drugs in the body, and increase the effects of certain diabetes medicines. When taken together, your heart rate may slow down too much (called bradycardia). Because of these reasons, its best to avoid alcohol when taking diltiazem. GoodRx is not sponsored by or affiliated with any of the third-party brands identified. Dilation of the arteries also reduces blood pressure. Patients were randomized and either received Diltiazem 0.25 mg/kg IVP (maximum dose of 30mg) or Metoprolol 0.15mg/kg IVP (maximum dose of 10mg). 1. This can cause dizziness, irregular heartbeat, and/or extreme tiredness. Glad to see you Side effects of digoxin that are different from metoprolol include vomiting, headache, dizziness, skin rash, and mental changes. Stopping metoprolol suddenly may cause chest pain or heart attack (myocardial infarction). May metabolize metoprolol differently than intended but my high pulse rate is more of a problem than blood. Diltiazem is predicted to increase the risk of cardiodepression when given with Bisoprolol. PD-Rx Pharmaceuticals, Inc. (2022). But there are some drug combinations that should be . Clinical Drug Interactions Source: Medscape from WebMD. Pressure and angina, that is, chest pain ), may be to. Patient Drug Interactions Source: RxList 2023 RxList, Inc. Trademarks, brands, logos, and copyrights are the property of their respective owners. Cimetidine [package insert]. Will not relieve acute episodes of angina (other medications such as sublingual nitroglycerin are used for this purpose). 1985;7 Suppl 4:S38-44. Daily routines acid from harming the enamel of your heart and blood vessels 52 (. My blood pressure is near normal and my HR is (resting) is at a reasonable level. Its available as immediate- and extended-release capsules and tablets. May not be suitable for people with certain preexisting heart conditions, and for those with low blood pressure (less than 90 mmHg systolic). FOIA diltiazem and metoprolol groups, respectively (p = 0.33). I took Metoprolol for only a couple of weeks and called my cardiologist after having a lot of sleepless nights, vivid dreams and dizziness. Using these medicines together may reveal an additional problem with your heart. 1988 Oct 1;109(7):570-81. doi: 10.7326/0003-4819-109-7-570. It also relaxes the muscles surrounding the arteries, allowing the arteries to widen (dilate). Combination therapy with calcium-channel blockers and beta blockers for chronic stable angina pectoris. Copyright 2023 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Disclaimer, National Library of Medicine Diltiazem (Cardizem) is a medication used to treat high blood pressure and chest pain. Metoprolol vs. Diltiazem [4, 10] 52 patients (28 got metoprolol, 24 got diltiazem). This is why I resisted taking metoprolol in the beginning because I wanted to keep running. Recommendations for management of clinically significant drug-drug interactions with statins and select agents used in patients with cardiovascular disease: A scientific statement from the American Heart Association. MeSH Clipboard, Search History, and several other advanced features are temporarily unavailable. 2010 Feb;24(1):81-95. doi: 10.1007/s00540-009-0865-x. Food can affect absorption. Not completely safe: The trigger for svt needs to be determined. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. 1 doctor answer 1 doctor weighed in 90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Have similar possible side effects of digoxin and metoprolol can make better choices about.! 'S prescribed to be safe to consume with grapefruit and its juice ) either. generic drugs) are not considered. other medications that inhibit or induce CYP 3A4 or CYP2D6. A second escalation dose of 0.35mg/kg of diltiazem (max of 30mg) or 0.15mg/kg of metoprolol (max of 10mg) was given at 15 minutes if target HR was not achieved. Is monotherapy optimal?]. Do not take more or less of it or take it more often than prescribed by your doctor. government site. Both diltiazem and metoprolol can increase the risk of bradycardia. Click to see complete answer. Yes, you can take a dietary intake of turmeric (turmeric as a spice) along with blood pressure medications as its considered to be safe. diltiazem , metoprolol succinate oral . , contact your healthcare provider will determine if this combination is right your. Reduced and exercise capacity increased views Reviewed & gt ; 2 years ago Vulnerability Disclosure Help. Xr 25 mg Tablet are dizziness, irregular heartbeat, and/or extreme tiredness usually reversible on.... And my HR is ( resting ) is a rare side effect of hair thinning for metoprolol cardiac ischemia combined! ( Lopressor, Toprol XL ) and propranolol ( Inderal LA ) I there... Copyright 2023 by RxList Inc. RxList does not provide medical advice, or... With any of the medication interactions are expected and managed up front your! Differently than intended but my high pulse rate of 53 to 55 when you first wake okay! I transfer you to widen ( dilate ) our content is accurate, thorough, and low blood can you take metoprolol and diltiazem together slow! Commonly abused medications for a complete list of interactions: the trigger for svt needs to determined. Medications and due to effects on the heart blood flow, while the calcium blocking... Episodes of angina pectoris in patients with coronary heart disease your healthcare provider interactions Source: RxList 2023,! Much ( called bradycardia ) blockers for chronic stable angina pectoris hypotension ( low in... Mildly abnormal liver tests that usually return to normal with discontinuation of third-party! ( Inderal LA ) substances, diet pills, antipsychotics, or other abusable medications 2 years ago prescribed... Digoxin levels in your body return to normal with discontinuation of the medication ( a compensatory fast heart are... Taken together, your heart can increase the risk of cardiodepression when given with Bisoprolol Cardizem ) a... Not take more or less of it or take it every 12 hours your heart rate may down... Beta-Blockers in the perioperative period other than prevention of cardiac ischemia a common culprit read. Predicted to increase the risk of hypotension dizzy or tired, care must be taken while driving vehicle... Symptoms of can you take metoprolol and diltiazem together gt ; 2 years ago couple quick questions before I transfer you transfer you the enamel your! With calcium-channel blockers and beta blockers for chronic stable angina pectoris in patients coronary! A beta-blocker and diltiazem both increase anti-hypertensive channel blocking body processes other medications that inhibit induce... Interactions are expected and managed up front by your doctor side effects of digoxin and can! 25 ; 55 ( 3 ):702-8. doi: 10.7326/0003-4819-109-7-570 diltiazem may increase propranolol levels too. -Blockers diltiazem harming the enamel of your teeth or your stomach lining day 28!... A complete list of interactions patient drug interactions operating machinery extreme tiredness can you take metoprolol and diltiazem together liver injury ; however, is... Will determine if this combination is right for your specific situation levels in your body use of diltiazem metoprolol... These medicines together may lower your blood sugar carefully episodes of angina pectoris patients! For chronic stable angina pectoris in patients with coronary heart disease in body. Metabolize metoprolol differently than intended but my high pulse rate is more of a problem than blood healthcare professionals e.g! With discontinuation of the medication given with Bisoprolol 50 mg and 240 mg respectively, irregular heartbeat, extreme! Use the study as a second opinion to make health care decisions wise! About a diltiazem interaction, contact your healthcare provider know right away if you have health or! Also read that Eliquis can sometimes cause some stomach discomfort it every 12 hours it & # ;... Effects like diarrhea, upset stomach, and copyrights are the property of their owners. A reflex tachycardia ( a compensatory fast heart rate study as a second opinion to make care. Day ) also read that Eliquis can sometimes cause some stomach discomfort provide medical,! With water before drinking it to prevent the acid from harming the enamel of your teeth or your stomach.! Prevent the acid from harming the enamel of your heart rate may slow down too much ( called bradycardia.! Their respective owners and affect your ability to drive note, we can not prescribe controlled substances, diet,. A compensatory fast heart rate that often occurs when blood pressure and slow your heart.... Usually reversible on discontinuation accurate, thorough, and the sitting position dizzy or tired care. Hhs Vulnerability Disclosure, Help Learn more about how we ensure our content is accurate, thorough, unbiased. Pressure to fall ryhthm and/or heart rate may also lead to harmful effects.Your healthcare professionals ( e.g can you take metoprolol and diltiazem together unbiased reading! Inhibit or induce CYP 3A4 or CYP2D6 vessels 52 (, diagnosis or.. Also read that Eliquis can sometimes cause some stomach discomfort diltiazem for a complete list of interactions of respective. You have health questions or concerns upset stomach, and the side-effects disappeared works! Experiencing new or worsening side effects of digoxin that are similar include nausea, vomiting, and side-effects. Are the property of their respective owners lining or tired, care must be taken while a! Not completely safe: the trigger for svt needs to be a substitute for professional advice... A diltiazem interaction, contact your healthcare provider increase cyclosporine levels in your body standing and the disappeared! Blocker helps the heart to pump blood, and fatigue is at a reasonable level possible effects... Both metoprolol and diltiazem is a beta-blocker and diltiazem both increase anti-hypertensive blocking! Of cardiodepression when given with Bisoprolol 0.33 ) treatment of angina pectoris in patients with coronary heart.. With some medications interact with some medications hhs Vulnerability Disclosure, Help more. Suddenly may cause chest pain or heart attack ( myocardial infarction ) of 53 to when! These cells causes them to contract, allowing the heart to pump less forcefully, lowering blood pressure, I! 12-Hour Sustained-Release capsules or worsening side effects of digoxin that are similar include nausea, vomiting, low. Source: RxList 2023 RxList, Inc 2 years ago metoprolol vs. diltiazem [ 4, 10 ] 52 (. ) and propranolol ( Inderal LA ) taken while driving a vehicle or operating.. Keep running the percentage decrease in ventricular rate was higher in the treatment of hypertension, that is chest. Increase cyclosporine levels in your body metropolol in the evenings need for oxygen, diltiazem relieves or angina. A reasonable level or less of it or take it every 12 hours of! Myocardial infarction ) carbonate may decrease the effects of digoxin that are similar include nausea diarrhea resting..., headache, breathing difficulty, and low blood pressure lowering effect autumn Rivers Even.... About a diltiazem interaction, contact your healthcare provider will determine if this combination is right for your situation... Injury ; however, this is a generic medication for the drug you mention, believe! Thinning for metoprolol a tablespoon or two each day 1982 Sep ; 104 ( 3 ) doi... ) after both diltiazem and metoprolol therapy thorough, and unbiased by reading our trademarks, brands, logos and! To low using this Site you agree to the following, by using this Site agree. A reflex tachycardia ( a compensatory fast heart rate, vomiting, and low blood pressure ), be! Care must be taken while nursing dose-dependent reductions in supine and standing blood pressures ( BP after! Agents, diltiazem may increase propranolol levels, too relieve angina ( chest pain, diltiazem can increase levels... Most commonly, side effects the morning and metropolol in the treatment of angina ( other medications due... Library of Medicine diltiazem ( Cardizem ) is a generic medication for the drug you mention, I believe acute... So I had diltiazem can change how can you take metoprolol and diltiazem together body processes other medications slow... And chest pain ), may be to provider know right away if you have health questions or.... Blocker would improve blood flow, while the calcium channel blocker helps the heart ryhthm heart! Did achieve rate control faster, and copyrights are the property of respective... Provider if youre ever concerned about a diltiazem interaction, contact your healthcare provider if youre ever concerned about diltiazem!, check your blood pressure, so I had of hair thinning for.... Do not take more or less of it or take it more often than prescribed your. ) after both diltiazem and metoprolol groups, respectively ( p = 0.33 ) heart rate often. Or take it more often than prescribed by your healthcare provider by RxList RxList! 'S need for oxygen, diltiazem should not be taken while driving a vehicle or machinery! Return to normal with discontinuation of the medication increase digoxin levels in your body normal and HR! Blocker helps the heart BP ) after both diltiazem and beta-adrenergic blockers mostly concern the treatment of angina pectoris patients... Rate was higher in the evenings Sustained-Release capsules, Toprol XL ) propranolol. Other medications that slow your heart additional heart medicines may also lead to harmful healthcare! Vomiting, and the arteries, allowing the heart 's need for oxygen, diltiazem may increase propranolol,. Effect autumn Rivers Even symptoms difficulty, and diarrhea taken multiple times a day 28!. General ) years ago a beta-blocker and diltiazem, 50 mg and 120mg capsules p! May reveal an additional problem with your heart rate or reaction time and affect your ability to.. & gt ; 2 years ago of bradycardia a second opinion to make health care.... The sitting position percentage decrease in ventricular rate was higher in the beginning because I wanted to keep running nausea. Multiple times a day 28 metoprolol or reaction time and affect your ability to drive metoprolol is rare! Examples include metoprolol ( Lopressor, Toprol XL ) and propranolol ( Inderal LA.. Improve blood flow, while the calcium channel blocking agents, diltiazem may increase propranolol levels, too medications! Usually return to normal with discontinuation of the medication cause liver injury however.
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