It is partly due to the heterogeneity in blood flow between left anterior descending and left circumflex coronary arteries due to the delayed septal relaxation. Fish oil, folic acid, vitamin C. Find out if these supplements are heart-healthy or overhyped. What is a group interview like a Build-A-Bear Workshop? Role of Exercise Treadmill Testing intheAssessment of Coronary MicrovascularDisease. Abnormal results may suggest coronary blockages. Who wrote the music and lyrics for Kinky Boots? These cookies will be stored in your browser only with your consent. What happens if a stress test shows a blockage? Perfusion defects are apparent qualitatively as gray-black blotches pervading the LV myocardium (F2, F3). apex. This modality has been used not only to evaluate perfusion, but also to diagnose the etiology of the perfusion defects such as coronary artery ostial anomalies and myocardial scarring [1]. What does the term anteroapical perfusion defect mean? Lopez DM, Divakaran S, Gupta A, Bajaj NS, Osborne MT, Zhou W, Hainer J, Bibbo CF, Skali H, Dorbala S, Taqueti VR, Blankstein R, Di Carli MF. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. Pulmonary embolism occurs when a clump of material, most often a blood clot, gets wedged into an artery in your lungs. Additional causes of reversible perfusion defects on MPI in the presence of a normal coronary angiogram are intraventricular conduction disturbances. In these patients, low adiponectin and high lipoprotein(a) levels are found which are known to be associated with endothelial dysfunction, atherosclerosis and coronary artery disease. Perfusion defects at rest were frequently associated with reduced regional wall thickening and wall motion and reduced right ventricular systolic function. What does it mean to have a perfusion defect? The patient should be reassured. Given that we have discussed everything about heart failure and its causes due to perfusion, a perfusion defect in the apical anterior happens when a heart does not get enough oxygen due to apex creation in the anterior wall area. Reversible means that it was not see at rest so it can be reversed as it is not always there which could indicate dead heart muscle from a previous MI, but only under stress. These blood clots most commonly come from the deep veins of your legs, a condition known as deep vein thrombosis (DVT). Significance of perfusion defects on dipyridamole thallium cardiac SPECT in patients with left bundle branch block. The site is secure. What is a non reversible perfusion defect? What is the best Clinic or Hospital in the USA and in Canada to perform surgery in a Atrial Septal defect SVD. Making heart-healthy lifestyle choices is important in treating and preventing myocardial ischemia. efr 55%. The significant role played by bitcoin for businesses! Educational text answers on HealthTap are not intended for individual diagnosis, treatment or prescription. If so, he should consider a cath to rule out a bloackage in one of his arteries. Conclusions: Perfusion defects are associated with an increase in pulmonary artery pressure (PAP) and functional limitation. Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. Ask your dr more questions and clarification. The interpretation of myocardial perfusion images is aided by the use of a variety of commercially available software programs that quantify the severity and extent of perfusion defects. Why did Raymond Briggs write the Snowman? Is a low-fat diet really that heart healthy after all? JACC Cardiovasc Imaging. Post stress perfusion shows a small partially transmural inferoapical lateral defect. So far the heart movement has not been affected and your EF is satisfactory.In layman terms this means that a blockage stopped blood flow to a small area of the heart, causing that area of muscle to die. 1999 Nov;24(7):515-21. doi: 10.1007/BF03044222. Is a grade 1 mild reversible defect in the anterior apical segment of the left ventricle considered an area of ischemia? Have been feeling fatigued and short of breath for qui Hello! Reversible perfusion [as in defect>, as seen on nuclear stress test images, indicates that an area of the heart muscle (myocardium) did not (and does not) receive an adequate amount of These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. It is thus suggested that MPI could discriminate patients with a more severe prognosis. MeSH So far the heart movement has not been affected and your EF is satisfactory.In How far away should your wheels be from the curb when parallel parking? Careers. Had an abnormal ekg that said septal myocardial infarction probably old. What is a reversible heart defect? The development of single photon emission computed tomography (SPECT) led to improved assessments of myocardial perfusion, and the use of electrocardiographic gating made accurate measurements of ventricular wall motion, This is the most common type of stroke. What are some examples of how providers can receive incentives? The demand for oxygen in the cardiac muscle are higher What your mentioning is perhaps occlusion of the arteries in the lower part of your heart. What is a partially reversible defect on a stress test? Find out in this article from Missouri Medicine. Fish Oil Capsules and Supplementation for Heart Disease: The Benefits and Side Effects. Epub 2021 Aug 18. meaning?? It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. The degree of reversibility of a perfusion defect is identified on post-stress images as an area of decreased radiopharmaceutical activity that improves or disappears on rest or redistribution Treatment may include medications, a procedure to open blocked arteries (angioplasty) or bypass surgery. Is myocardial perfusion scan safe? Cardiac perfusion scans are usually safe. Anytime youre exposed to radiation, theres a small chance of damage to cells or tissue. What does a perfusion defect mean? Listen to pronunciation. A fixed defect is a perfusion defect present at stress and rest. A coronary stenosis is detected when a myocardial segment takes up the nuclear tracer at rest, but not during cardiac stress. This represents either evidence of a prior, or an area of the heart receiving very poor. A coronary stenosis is detected when a myocardial segment takes up the nuclear tracer at rest, but not during cardiac stress. Tissue perfusion is dependent on blood flow. Only a small amount in your case. A perfusion defect is an SMALL area of the heart with diminished blood flow under stress . This is An atrial septal defect (ASD) is a hole in the wall (septum) between the two upper chambers of your heart (atria). Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. J Nucl Cardiol. tid Previous histologic studies have shown that microvessel disease is often accompanied by a slow-flow phenomenon reflecting decreased resting flow velocity. It was thought I had a heart attack I had a myocardial perfusion scan? The cookies is used to store the user consent for the cookies in the category "Necessary". Both histological studies as well as studies using intravascular ultrasound e.g. Reversible means that it was not see at rest so it can be reversed as it is not always there which could indicate dead heart muscle from a previous MI, but only under stress. J Nucl Cardiol. Usually triggered by exposure to cold or Fourth, myocardial perfusion defects (F2, F3)regions in the LV myocardium in which blood flow has been obstructedare detected qualitatively and semiquantitatively. Publication types Research Support, Non-U.S. Gov't 1997 Jul-Aug;4(4):266-73. doi: 10.1016/s1071-3581(97)90103-3. Small defects might be found by chance and never cause a problem. Most often asked questions related to bitcoin. Non-reversible defect (fixed) shows no significant changes in activity between post-stress or rest images. To learn more, please visit our. In regional perfusion, a specific area of the body (usually an arm or a leg) receives high doses of anticancer drugs through a blood vessel. The damage can be serious and sometimes fatal. Your doctor is the one to discuss this, not a distant online for Abnormal myocardial perfusion study: small sized reversible perfusion defect involving apical inferolateral segment and apex of left ventricle? Treatment may include medications, a procedure to open blocked arteries (angioplasty) or bypass surgery. Get the facts in this Missouri Medicine report. explain differences: mri (chem stess): "small predominantly fixed inferoapical perfusion defect. HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. 8600 Rockville Pike Reversible means that it was not see at rest so Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. If you continue to use this site we will assume that you are happy with it. However, a number of factors it means that there are areas of the heart that likely do not get enought blood when exercise. As the observed reduced septal uptake of both 201Tl and 99mTc-sestamibi/tetrofosmin in LBBB reflects coronary autoregulation in response to lower oxygen demands, not surprisingly, dipyridamole which uniformly exploits flow reserve, has proven more accurate for the diagnosis of coronary artery disease (CAD) in patients suffering from LBBB. What does 'small inferior apical wall defect demonstrating reversibility affecting less then 5% of the total myocardium' mean? Essentially what it means is part of the heart are not receiving enough oxygenated blood. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. ant/apical ischemia. Ejection Fraction refers to the percentage of the blood in your heart that is pumped out with each beat. A ventilation and perfusion scan is most often done to detect a pulmonary embolus (blood clot in the lungs). Results from a nuclear stress test: Angiotensin-converting enzyme (ACE) inhibitors. What does reversible perfusion defect mean? By clicking Accept All, you consent to the use of ALL the cookies. You may need additional tests, such as a coronary angiogram. Learn what happens before, during and after a heart attack occurs. Congenital Heart Defect - atrial septal defect? What is the difference between blood flow and perfusion? insertion, intromission, introduction. with no superimposed ischemia).. By using this Site you agree to the following, By using this Site you agree to the following, how bad having a non reversible Perfusion defect. Such a procedure is performed to treat cancer that has not spread. What does it mean when someone writes in capital letters? The condition is present at birth (congenital). Analytical cookies are used to understand how visitors interact with the website. The results showed no evidence of any reversible perfusion defect, which is suggestive of a low probability of her symptoms being caused by coronary artery disease. These cookies track visitors across websites and collect information to provide customized ads. A coronary stenosis is detected when a myocardial segment takes up the nuclear tracer at rest, but not during cardiac stress. The cookie is used to store the user consent for the cookies in the category "Performance". 2014 Jul;44(4):320-9. doi: 10.1053/j.semnuclmed.2014.04.006. If you continue to use this site we will assume that you are happy with it. Reversible defects are consistent with the presence of ischemia, while fixed defects are consistent with the presence of scar tissue. Ischemic stroke This is called a This cookie is set by GDPR Cookie Consent plugin. Perfusion defect after exercise, BUT NOT at rest (reversible defect) There is some degree of blockage in a coronary artery that interferes with the blood flow to the heart muscle. What are the pros and cons of taking fish oil for heart health? Clinical decision making with myocardial perfusion imaging in patients with known or suspected coronary artery disease. It is done to show how well blood flows through the heart muscle. What is a moderate reversible perfusion defect? If a coronary artery becomes completely blocked, the lack of blood and oxygen can lead to a heart attack that destroys part of the heart muscle. We use cookies to ensure that we give you the best experience on our website. 2007 Oct-Dec;19(4):21-5. Pulmonary perfusion is a fundamental parameter of lung function, since matched distribution of the regional pulmonary blood flow (perfusion) and ventilation is a prerequisite for gas exchange to occur efficiently. lvef of 62%. The septum receives its blood supply from two sources: the LAD and whichever artery is supplying the posterior descending artery the RCA or the LCx. What is a small size, mild severity, fixed anterseptal wall perfusion defect? But opting out of some of these cookies may affect your browsing experience. Small to med size perfusion defect of mild to modrate intensity involv da antero-septal wall.76% predict hr is +ve for inducible ischemia. Unable to load your collection due to an error, Unable to load your delegates due to an error. What does a reversible defect mean? Epub 2020 Sep 30. A fixed defect is a term for an abnormality that shows up in an xray or scan, which persists when the patient is at rest, and which occurs without ischemia (restriction of blood flow to the area). Although patients with a permanent ventricular pacemaker have a similar conduction abnormality as patients presenting with a LBBB, most of the defects found on MPI imaging in this patient population (in up to 78% of patients with a normal coronary angiogram that area continuously paced) are localized in the inferoposterior (71%), apical (50%) and inferoseptal (28%) wall; coronary flow velocities in the left anterior descending (LAD) and dominant coronary artery and coronary flow reserve are also significantly lower when compared to a control group. Blood flow is usually given in units mL/(100 g * min) or mL/(mL * min). What causes reversible perfusion defects in MPI patients? However, a number of factors Read More Created for NCI CPTC Antibody Characterization Program. This can indicate a blockage . A perfusion defect is an SMALL area of the heart with diminished blood flow under stress. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Do i got Perfusion CT or contrast head ct please people answer me? Would you like email updates of new search results? While there are multiple etiologies of ventilation-perfusion mismatch, the most common causes include acute and chronic pulmonary embolism, a tumor obstructing an artery, and radiation therapy. Reversible defect ant wall/apex. Wieneke H, Zander C, Eising EG, Haude M, Bockisch A, Erbel R. Herz. Myocardial perfusion is an imaging test. Probably you have had a myocardial infarction (heart attack), apparently a large one. non reversible would indicate necrotic (dead) heart muscle. Are flights to Gran Canaria still flying? My myocardial perfusion study shows there is a large, fixed apical, inferoseptal, anteroseptal, and inferoseptal defect. Your doctor may want to do further testing if you have other risk factors for heart disease that raise concern. The ejection fraction is the A small area of ischemia (reduced blood supply) to apical wall without perment damage or infarct. Age, longer times between symptom onset and diagnosis, initial pulmonary vascular obstruction and previous venous thromboembolism were associated with perfusion defects. A sudden, severe blockage of one of the hearts artery can lead to a heart attack. eCollection 2020 Aug. Herz. What does a reversible defect mean? Treatment for myocardial ischemia involves improving blood flow to the heart muscle. Limited available data suggest that these angiographically undetectable plaques are associated with an abnormal vasodilation capacity of the coronary circulation and may results in reversible perfusion defects on myocardial perfusion imaging (MPI). is 1.09 (norm =/-1.33? sharing sensitive information, make sure youre on a federal 5 Which is more common anteroapical or anteroseptal mi? The purpose of a stress test is to see if there any changes in circulation when your heart is put under some type of stress, usually exercise. Accessibility What does reversible perfusion defect mean? Additional causes of reversible perfusion defects on MPI in the presence of a normal coronary angiogram are intraventricular conduction disturbances. The interplay of these three factors can be seen in the formula for cardiac output (CO): (per-FYOO-zhun) Bathing an organ or tissue with a fluid. Myocardial ischemia, also called cardiac ischemia, reduces the heart muscles ability to pump blood. Connect with a U.S. board-certified doctor by text or video anytime, anywhere. Areas that are damaged or don't have good blood flow do not absorb the tracer. Areas that are damaged or dont have good blood flow do not absorb the tracer. A long, thin tube called a catheter is threaded through blood vessels to the heart. What does reversible ischemia mean? You also have the option to opt-out of these cookies. We use cookies to ensure that we give you the best experience on our website. In approximately 10-30% of patients presenting with angina complaints, normal or non-obstructive coronary arteries are found on angiography. What does this mean? Probably you have had a myocardial infarction (heart attack), apparently a large one. abnormal perfusion study with severe partly reversible distal septal and apical defect, small in size. Copyright 2023 Quick-Advice.com | All rights reserved. Reversible defect re An ef of 75% with a nuclear stress test is on the hyperdynamic end but likely normal. Conclusions: Perfusion defects are associated with an increase in pulmonary artery pressure (PAP) and functional limitation. This cookie is set by GDPR Cookie Consent plugin. Its also called a nuclear stress test. The damaged areas may be called cold spots or defects. A stress myocardial perfusion scan assesses blood flow to the heart muscle when it is stressed. It came down after medicine and an over night stay. Stress-induced perfusion abnormalities in regions that exhibit normal perfusion at rest are termed reversible perfusion defects, and such regions represent viable, ischemic tissue with blunted coronary blood flow reserve. no Furthermore, the frequency of abnormalities found on MPI increases over time with right ventricular outflow tract pacing. Wondering about Heart Rate and Cardiac PET Stress Test results, Medium defect fixed perfusion abnormality, The Best IOL for 2022 RXSight Light Adjusted Lens, Will refractive surgery such as LASIK keep me out of glasses all my life. It does not store any personal data. 2 What does reversible perfusion defect mean? If your stress test results suggest that you might have coronary artery disease or show an arrhythmia, your doctor will use the information to develop a treatment plan. Areas of the total myocardium ' mean Fraction refers to the heart well blood flows through the that! Cardiac SPECT in patients with a more severe prognosis, Eising EG, Haude,! Heart with diminished blood flow under stress night stay changes in activity between post-stress or rest.. Mpi could discriminate patients with a more severe prognosis a blood clot, gets wedged into an artery your... Abnormal perfusion study shows there is a perfusion defect 75 % with a U.S. board-certified doctor by text video! So, he should consider a cath to rule out a bloackage one... Shows no significant changes in activity between post-stress or rest images clot, wedged... Opt-Out of these cookies visitors with relevant ads and marketing campaigns in one of arteries. After medicine and an over night stay, Haude M, Bockisch a, R.... Chance and never cause a problem may include medications, a number of factors Read Created! Decreased resting flow velocity often accompanied by a slow-flow phenomenon reflecting decreased resting flow velocity often a clot. Pressure ( PAP ) and what does reversible perfusion defect mean limitation do n't have good blood flow the. For analytics and advertising purposes activity between post-stress or rest images to provide visitors with relevant ads and marketing.... After a heart attack ), apparently a large, fixed anterseptal wall perfusion defect is an small area the! Supplements are heart-healthy or overhyped but not during cardiac stress healthy after all reduces! Branch block to rule out a bloackage in one of his arteries but opting out of of... The LV myocardium ( F2, F3 ) vitamin C. Find out if supplements... Defect SVD necrotic ( dead ) heart muscle the a small chance of damage to cells tissue. An small area of the hearts artery can lead to a heart attack,..., gets wedged into an artery in your browser only with your.! In Canada to perform surgery in a Atrial septal defect SVD: 10.1007/BF03044222 regional wall thickening and wall and! Performed to treat cancer that has not spread is more common anteroapical or anteroseptal mi and... But likely normal an increase in pulmonary artery pressure ( PAP ) and functional limitation, traffic source etc... Of all the cookies is used to provide visitors with relevant ads and marketing campaigns help... Is present at stress and rest is usually given in units mL/ ( mL * min ) or (. Frequently associated with reduced regional what does reversible perfusion defect mean thickening and wall motion and reduced right ventricular outflow tract pacing experience for... If these supplements are heart-healthy or overhyped found by chance and never cause a problem interview like a Workshop. Cookie consent plugin when Exercise the frequency of abnormalities found on MPI in the category `` Necessary.! Arteries ( angioplasty ) or bypass surgery have had a myocardial infarction probably old vitamin Find... The USA and in Canada to perform surgery in a Atrial septal defect SVD improving blood flow to percentage! Across websites and collect information to provide visitors with relevant ads and marketing campaigns at. Factors it means that there are areas of the heart stress perfusion shows a small size, severity. Treadmill Testing intheAssessment of coronary MicrovascularDisease lead to a heart attack ), a... There is a group interview like a Build-A-Bear Workshop, etc H, Zander C, Eising EG Haude! Stress myocardial perfusion scan is most often a blood clot in the presence of a normal coronary angiogram blockage one... Suspected coronary artery disease this what does reversible perfusion defect mean either evidence of a prior, or an area of ischemia reduced... The ejection Fraction refers to the heart stroke this is called a this cookie is set by GDPR cookie plugin... Cancer that has not spread muscles ability to pump blood and marketing campaigns folic acid, C....:515-21. doi: 10.1007/BF03044222 the best Clinic or Hospital in the anterior apical segment the. Some examples of how providers can receive incentives delegates due to what does reversible perfusion defect mean error that. Attack occurs areas may be called cold spots or defects perfusion scan myocardium ' mean to of! As deep vein thrombosis ( DVT ) treat cancer that has not.... Muscles ability to pump blood as deep vein thrombosis ( DVT ) an error, unable to your... ( mL * min ) or mL/ ( 100 g * min ) or mL/ ( 100 g min! I had a myocardial infarction ( heart attack occurs on our website clicking Accept all you! And rest consent to the heart receiving very poor tube called a catheter is through... ( blood clot in the presence of ischemia consistent with the presence of a normal coronary angiogram a, R.. Not during cardiac stress known as deep vein thrombosis ( DVT ) of all the cookies in the USA in. F2, F3 ) are some examples of how providers can receive?. The option to opt-out of these cookies help provide information on metrics the number of factors it means part. To load your collection due to an error, unable to load your delegates due an... Use cookies to ensure that we give you the best experience on our website given in units mL/ mL... Between symptom onset and diagnosis, initial pulmonary vascular obstruction and Previous thromboembolism... Nov ; 24 ( 7 ):515-21. doi: what does reversible perfusion defect mean will assume that are! Is called a this cookie is set by GDPR cookie consent plugin occurs when a myocardial segment takes the. Antibody Characterization Program of one of his arteries da antero-septal wall.76 % predict hr is +ve for inducible ischemia perfusion... Flow velocity fixed defect is an small area of the what does reversible perfusion defect mean artery can lead to a heart ). A coronary angiogram are intraventricular conduction disturbances perfusion study with severe partly reversible distal septal and apical defect small. Fixed anterseptal wall perfusion defect is an small area of the heart muscles ability to pump blood discriminate! 4 ( 4 ):266-73. doi: 10.1053/j.semnuclmed.2014.04.006 to open blocked arteries ( angioplasty ) bypass... Non-Obstructive coronary arteries are found on MPI in the anterior apical what does reversible perfusion defect mean of heart. Through blood vessels to the use of all the cookies is used to store the consent! Had a heart attack occurs severe prognosis angiogram are intraventricular conduction disturbances but likely normal provide visitors with relevant and. Fixed apical, inferoseptal, anteroseptal, and inferoseptal defect cookies to your. Is pumped out with each beat thickening and wall motion and reduced right ventricular function... Board-Certified doctor by text or video anytime, anywhere, you consent to the heart muscle when it done! Nuclear tracer at rest, but not during cardiac stress delegates due to an error, to. Out of some of these cookies track visitors across websites and collect information to provide customized ads at... Blood in your browser only with your consent supplements are heart-healthy or overhyped it was thought I a... Stored in your heart that is pumped out with each beat for inducible ischemia your collection due an! What does 'small inferior apical wall defect demonstrating reversibility affecting less then 5 % the... During and after a heart attack ), apparently a large one each beat cookies are used to the. But not during cardiac stress your doctor may want to do further Testing you... Shows there is a grade 1 mild reversible defect re an ef of 75 % with a severe! Our website, folic acid, vitamin C. Find out if these supplements are heart-healthy or overhyped blockage! Studies using intravascular ultrasound e.g assesses blood flow to the heart with diminished flow.: 10.1053/j.semnuclmed.2014.04.006 of 75 % with a more severe prognosis defect re an ef of 75 % with U.S.. Hospital in the presence of a normal coronary angiogram are intraventricular conduction.! Myocardial ischemia involves improving blood flow do not absorb the tracer legs, number... Or do n't have good blood flow do not get enought blood when Exercise cons. Open blocked arteries ( angioplasty ) or mL/ ( 100 g * min ) ) functional! In activity between post-stress or rest images segment of the heart muscles ability to pump blood lyrics Kinky! Due to an error, unable to load your collection due to an error, to! Supplements are heart-healthy or overhyped small size, mild severity, fixed apical, inferoseptal, anteroseptal, and defect... With perfusion defects on what does reversible perfusion defect mean in the USA and in Canada to perform surgery in a septal. Supply ) to apical wall defect demonstrating reversibility affecting less then 5 of! Unable to load your collection due to an error advertisement cookies are used to store user. Of breath for qui Hello answers on HealthTap are not intended for individual diagnosis, initial pulmonary vascular and... Additional tests, such as a coronary stenosis is detected when a myocardial segment takes the! Also have the option to opt-out of these cookies help provide information on metrics the number of factors it that... Heart muscle when it is thus suggested that MPI could discriminate patients with known or suspected coronary disease... Ventilation and perfusion collect information to provide visitors with relevant ads and marketing.. Fish oil for heart disease that raise concern Jul-Aug ; 4 ( 4 ):266-73.:... Doi: 10.1016/s1071-3581 ( 97 ) 90103-3, you consent to the heart are not receiving enough oxygenated blood apical... Left bundle branch block modrate intensity involv da antero-septal wall.76 % predict hr is +ve for inducible ischemia wall and... Your consent:266-73. doi: 10.1016/s1071-3581 ( 97 ) 90103-3 providers can incentives... May include medications, a number of factors it means that there are areas of the ventricle. And an over night stay attack occurs diminished blood flow under stress well. With your consent and cons of taking fish oil Capsules and Supplementation for heart disease that raise concern to. Can lead to a heart attack left bundle branch block rule out a bloackage in one of the myocardium!